nova-ethanol

byyael tzror

ethanol, those lacking the tail domain exhibited a less dense network (Figure S1). This observation suggests that the tail domain may facilitate contacts between neighboring nanofilaments, contributing to a more cohesive internal structure. Importantly, since nanofibrils still formed in constructs without the tail (Ben-Harush et al., 2020), the observed aggregation phenomena under Ca²⁺ conditions are likely due to reduced connectivity rather than a failure of fibril formation itself. This reduced inter-fibril connectivity may limit interactions between neighboring fibrils, preventing the establishment of a continuous and mechanically stable network, which is consistent with the aggregation observed for these constructs under ion-mediated conditions.